Center for Neurobehavioral Genetics

CNG Workshop: “An Overview of Single Cell RNA Sequencing: From Soup to Nuts”

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

The Center for Neurobehavioral Genetics will be hosting a computational workshop: “An Overview of Single Cell RNA Sequencing from Soup to Nuts.” Speakers include Drs. Mike Gandal, Dan Geschwind, Chongyuan Luo, Tim Stuart, Brie Wamsley, and Ms. Yi Zhang. While this event is provided as part of the Training Program in Neurobehavioral Genetics, it is […]

NBG Journal Club: Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines Article Link: https://www.sciencedirect.com/science/article/pii/S089662732100427X?via%3Dihub Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

ICNG Seminar: “Myogenesis: What’s neural got to do with it?”

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

April Pyle, Ph.D. Professor and Vice Chair Department of Microbiology, Immunology, and Molecular Genetics (MIMG) UCLA George and Nouhad Ayoub Centennial Chair for Life Science Innovation UCLA

NBG Journal Club: Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence Article Link: https://acamh.onlinelibrary.wiley.com/doi/epdf/10.1111/jcpp.13422 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

NBG Journal Club: A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy Article Link: https://www.pnas.org/content/119/6/e2118688119 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

NBG Journal Club: Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic:Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level Article Link: https://www.nature.com/articles/s41593-021-00999-y Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

NBG Journal Club: Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset Article Link: https://www.nature.com/articles/s41593-022-01033-5 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

NBG Journal Club: Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk Article Link: https://scholar.harvard.edu/files/tge/files/transcriptional_and_imaging-genetic_association_of_cortical_interneurons_brain_function_and_schizophrenia_risk.pdf Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

Trainee Research Talk: Investigation of mitochondrial dysfunction mechanisms in Rett syndrome neurons

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

In lieu of our typical Journal Club meeting, we will have a predoctoral trainee present on the research they have been conducting under the Training Program in Neurobehavioral Genetics. Research Topic: Investigation of mitochondrial dysfunction mechanisms in Rett syndrome neurons Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

ICNG Seminar: “What has 20 years of imaging genetics taught us about the brain?”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

David Glahn, PhD Associate Chief for Research Department of Psychiatry and Behavioral Sciences Director, Tommy Fuss Center for Neuropsychiatric Disease Research Boston Children’s Hospital Professor of Psychology in Psychiatry Harvard Medical School

NBG Journal Club: Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic:Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel Article Link: https://jamanetwork.com/journals/jamaneurology/fullarticle/2771828 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

ICNG Seminar: “Comparing living and postmortem human brain biology”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

Alexander Charney, MD, PhD Associate Professor Departments of Psychiatry and Genetics & Genomic Sciences Director, Charles Bronfman Institute for Personalized Medicine Icahn School of Medicine at Mount Sinai

NBG Journal Club: Relationship Between Sleep Duration and Cognitive Function in Older Adults: Analysis of NHANES and UK Biobank GWAS Data

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: Relationship Between Sleep Duration and Cognitive Function in Older Adults: Analysis of NHANES and UK Biobank GWAS Data Article Link: https://journals.sagepub.com/doi/10.1177/10998004241230325?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

ICNG Seminar: “Autophagy and neurodegeneration”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

David C Rubinsztein MB ChB, BSc(Hons), PhD, FRCPath, FMedSci, FRS Professor of Molecular Neurogenetics Deputy Director, Cambridge Institute for Medical Research UK Dementia Research Institute Professor Honorary Consultant, Department of Medical Genetics Cambridge Institute for Medical Research

ICNG Seminar: “Gene-environment interplay in psychiatric risk and resilience”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

Karmel Choi, PhD Assistant Professor, Harvard Medical School Director, Precision Prevention Program, MGH Center for Precision Psychiatry Psychologist, Department of Psychiatry, Massachusetts General Hospital

NBG Journal Club: Vision-dependent specification of cell types and function in the developing cortex

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: Vision-dependent specification of cell types and function in the developing cortex Article Link: https://www.cell.com/cell/fulltext/S0092-8674(21)01485-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867421014859%3Fshowall%3Dtrue Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

NBG Journal Club: The impact of assortative mating, participation bias and socioeconomic status on the polygenic risk of behavioural and psychiatric traits

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: The impact of assortative mating, participation bias and socioeconomic status on the polygenic risk of behavioural and psychiatric traits Article Link: https://doi.org/10.1038/s41562-024-01828-5 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

NBG Journal Club: Topic TBD

Virtual (Zoom) : https://uclahs.zoom.us/j/2970582103

Discussion Topic: TBD Article Link: TBD Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu

ICNG Seminar: “Future-proofing Neural Morphology”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

Giorgio Ascoli, PhD Professor Bioengineering & Neuroscience Krasnow Institute for Advanced Study George Mason University

ICNG Seminar: “Connecting electrophysiological measures from schizophrenia patient-derived neurons to the donor’s clinical status and cognitive performance”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

Brady J. Maher, PhD Lead Investigator, Lieber Institute for Brain Development Associate Professor, Dept. of Psychiatry and Behavioral Sciences Associate Professor, Dept. of Neuroscience Johns Hopkins University School of Medicine

ICNG Seminar: “Developmental Emergence of Personality”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

Bassem Hassan, PhD Scientific Director & Deputy Executive Director, Institut du Cerveau – Paris Brain Institute

ICNG Seminar: “Schizophrenia Risk Convergence in Gene Co-Expression Networks”

Gonda (Goldschmeid) Center, Room 1357 695 Charles E Young Dr, Los Angeles, CA, United States

Giulio Pergola, PhD Investigator, Lieber Institute for Brain Development, Baltimore, MD Associate Professor of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD Associate Professor of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD Professor of Neuropsychology and Cognitive Neuroscience, Department of Translational Biomedicine and Neuroscience, University of Bari Aldo […]

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