Genevieve Konopka, PhD Associate Professor, Department of Neuroscience Jon Heighten Scholar in Autism Research UT Southwestern Medical Center
The Center for Neurobehavioral Genetics will be hosting a computational workshop: “An Overview of Single Cell RNA Sequencing from Soup to Nuts.” Speakers include Drs. Mike Gandal, Dan Geschwind, Chongyuan Luo, Tim Stuart, Brie Wamsley, and Ms. Yi Zhang. While this event is provided as part of the Training Program in Neurobehavioral Genetics, it is […]
Robert Bilder, PhD Professor Department of Psychiatry & Biobehavioral Genetics UCLA
Discussion Topic: A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies Article Link: https://doi.org/10.1038/s41593-021-00913-6 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Brent Fogel, PhD Associate Professor Department of Neurology UCLA
Discussion Topic: Prognostic value of polygenic risk scores for adults with psychosis Article Link: https://www.nature.com/articles/s41591-021-01475-7 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Discussion Topic: Spatially mapped single-cell chromatin accessibility Article Link: https://www.nature.com/articles/s41467-021-21515-7.pdf Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Aparna Bhaduri, PhD Associate Professor Department of Biological Chemistry UCLA
Discussion Topic: Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines Article Link: https://www.sciencedirect.com/science/article/pii/S089662732100427X?via%3Dihub Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Avishek Adhikari, Ph.D. Assistant Professor of Behavioral Neuroscience Department of Psychology UCLA
April Pyle, Ph.D. Professor and Vice Chair Department of Microbiology, Immunology, and Molecular Genetics (MIMG) UCLA George and Nouhad Ayoub Centennial Chair for Life Science Innovation UCLA
The Training Program in Neurobehavioral Genetics, directed by Drs. Roel Ophoff and Carrie Bearden, is accepting applications for Postdoctoral Trainees. Earliest funding is expected to begin 5/1/2022. In keeping with the program's goals, preference will be given to applicants who are trained in psychiatry, neurology, or psychology, although we also seek outstanding applicants with other […]
Discussion Topic: Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence Article Link: https://acamh.onlinelibrary.wiley.com/doi/epdf/10.1111/jcpp.13422 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Discussion Topic: Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model Article Link: https://www.nature.com/articles/s41593-020-00720-5 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Marieke Klein, PhD Postdoctoral Researcher Department of Psychiatry UCSD
Discussion Topic: Demographic history mediates the effect of stratification on polygenic scores Article Link: https://elifesciences.org/articles/61548 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Chun Chieh Fan, PhD Assistant Adjunct Professor Radiology UCSD
Discussion Topic: A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy Article Link: https://www.pnas.org/content/119/6/e2118688119 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Devanand S. Manoli, MD, PhD Assistant Professor, Psychiatry Weill Institute for Neurosciences UCSF
Discussion Topic: Make war not love: The neural substrate underlying a state-dependent switch in female social behavior Article Link: https://www.sciencedirect.com/science/article/pii/S0896627321009958 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Hui Zheng, PhD Professor & Huffington Foundation Endowed Chair in Aging Director, Huffington Center on Aging Baylor College of Medicine
Discussion Topic: Modeling assortative mating and genetic similarities between partners, siblings, and in-laws Article Link: https://www.nature.com/articles/s41467-022-28774-y Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Kwanghun Chung, PhD Department of Chemical Engineering Institute for Medical Engineering and Science (IMES) Picower Institute for Learning and Memory MIT
Discussion Topic:Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level Article Link: https://www.nature.com/articles/s41593-021-00999-y Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Discussion Topic: Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset Article Link: https://www.nature.com/articles/s41593-022-01033-5 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Discussion Topic: Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk Article Link: https://scholar.harvard.edu/files/tge/files/transcriptional_and_imaging-genetic_association_of_cortical_interneurons_brain_function_and_schizophrenia_risk.pdf Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
In lieu of our typical Journal Club meeting, we will have a predoctoral trainee present on the research they have been conducting under the Training Program in Neurobehavioral Genetics. Research Topic: Investigation of mitochondrial dysfunction mechanisms in Rett syndrome neurons Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Na Cai, PhD Principal Investigator Helmholtz Pioneer Campus Helmholtz Zentrum München
The Training Program in Neurobehavioral Genetics, directed by Drs. Roel Ophoff and Carrie Bearden, is accepting applications for Predoctoral Trainees. Earliest funding is expected to begin 9/1/2022. Proposed projects must have relevance to neurobehavioral genetics. A trainee’s appointment is contingent upon their mentor’s commitment to providing supplemental funding for Years 1 and 2 of the […]
Discussion Topic: Causal effects on complex traits are similar across segments of different continental ancestries within admixed individual Article Link: https://doi.org/10.1101/2022.08.16.22278868 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Discussion Topic: Causal effects on complex traits are similar across segments of different continental ancestries within admixed individual Article Link: https://www.science.org/doi/10.1126/science.abq5011 Zoom URL: Provided upon request from CNGT32@mednet.ucla.edu
Carolina Makowski, PhD Postdoctoral Scholar Department of Radiology UCSD
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